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Functional Nutrition

High uric acid? The cause may be intestinal dysbiosis.

November 2, 2025
Updated September 20, 2026
4 min read
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High uric acid? The cause may be intestinal dysbiosis.
Intestinal dysbiosis occurs when there is an imbalance between beneficial and harmful bacteria...

Intestinal Dysbiosis and Uric Acid: How Does Gut Health Affect Uric Acid Levels? 🧬

An imbalance between beneficial and harmful bacteria in the gut can be caused by several factors, such as poor diet, excessive use of antibiotics, stress, among others. When the gut microbiota is unbalanced, various health problems can arise, including elevated uric acid.

In short: High uric acid isn't always a kidney problem — part of its elimination happens through the intestines, so gut dysbiosis can be an overlooked cause of elevated levels even without a diet high in purine-rich foods. Rebalancing gut bacteria through fiber, probiotics, and hydration can help bring uric acid levels down.

How Does Dysbiosis Affect Uric Acid Levels? 🤔

Uric acid is a byproduct of the metabolism of purines, compounds found in certain foods and also produced by our body. Normally, it is eliminated by the kidneys, but when levels are high, it can accumulate in the joints, causing gout, or in the kidneys, forming stones.

It's common for patients to arrive with abnormal test results, and when I ask about their diet, they don't report high consumption of foods rich in purines, such as excess protein, processed meats, and organ meats, for example. Most of the time, we associate uric acid elimination solely with the kidneys, but part of the excretion of this compound occurs through the intestines. The patient's problem may not be renal but intestinal.

Furthermore, some bacterial strains increase the production of uremic toxins, worsening the situation even more. This patient may have intestinal dysbiosis, and because of this, elimination is not being done properly. Treating this condition will be extremely important to improve all the patient's health parameters.

Common Symptoms of Gut Dysbiosis 🌟

  • Abdominal distension and gas
  • Diarrhea or constipation
  • Chronic fatigue
  • Abdominal pain
  • Skin problems, such as acne or eczema
  • Sensitivity to certain foods

If you are experiencing these symptoms along with elevated uric acid levels, it may be a sign that your gut health needs attention.

Practical Tips 🌿

To rebalance your gut microbiota and help control uric acid levels, consider the following tips:

  • High-Fiber Diet: Include more fruits, vegetables, legumes, and whole grains in your diet. Fiber feeds the beneficial bacteria in the gut.
  • Probiotics and Prebiotics: Consume foods rich in probiotics, such as yogurt, kefir, and sauerkraut, and prebiotics, such as garlic, onions, and asparagus, to promote the growth of healthy bacteria.
  • Adequate Hydration: Drink plenty of water to help eliminate uric acid and keep your gut functioning well.
  • Reduce Processed Foods: Avoid foods high in sugar, trans fats, and artificial additives, which can harm gut health.
  • Stress Management: Practice relaxation techniques, such as meditation, yoga, or physical exercise, to reduce the impact of stress on your gut health.

Conclusion

High uric acid may have a direct connection to intestinal dysbiosis. Taking care of your gut health can be a crucial step in controlling these levels and improving your overall well-being. If you are experiencing problems with high uric acid, consider evaluating your gut health and making the necessary changes to your diet and lifestyle. Remember to consult a healthcare professional for personalized guidance tailored to your specific case.

Taking care of your gut is taking care of your whole body. Don't underestimate the power of a balanced gut microbiota to keep your body healthy and functioning optimally.

FAQ

Can gut health affect uric acid levels?

Yes — part of uric acid elimination happens through the intestines, so an imbalanced gut microbiota (dysbiosis) can impair this process and raise uric acid.

What foods should I avoid if I have high uric acid?

Excess protein, processed meats, and organ meats are common dietary triggers to limit.

What are signs of gut dysbiosis?

Abdominal bloating and gas, diarrhea or constipation, chronic fatigue, abdominal pain, and skin issues like acne or eczema are common signs.

How can I lower uric acid naturally through diet?

A high-fiber diet, probiotic and prebiotic foods, adequate hydration, and reducing processed foods all support both gut health and uric acid regulation.

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Bruna Barbosa

About the Author

Bruna Barbosa — Nutritionist, CRN-DF 16963

Specializing in Functional Nutrition, Phytotherapy, and Digestive Health, Bruna helps people understand their symptoms and transform their health starting from the gut, based on scientific evidence, empathy, and clinical practice. She produces accessible, well-founded content to guide more conscious and sustainable choices.

Learn more about Bruna →